Pan.bio Journal Club: How do Levantine genomes respond to medicines? Led by Nagham Nafiz Hendi
Population-scale catalogue of clinically actionable pharmacogenomic variation in a large Middle Eastern Levantine cohort
Led by Nagham Nafiz Hendi, first author of the study
About the session
The same drug at the same dose can work well for one patient and cause harm in another, and part of that difference is written in our genes. Most of what we know about these drug-response variants comes from European populations, which leaves a gap for patients in our region.
This new study catalogues clinically actionable pharmacogenomic variants across a large Levantine cohort, showing how common they are and which medicines they affect. Nagham will walk us through how the catalogue was built, what stood out, and what it could mean for prescribing in the Levant.
We'll talk about:
What pharmacogenomics is and why population matters
Key findings from the Levantine cohort
What this could change in everyday prescribing
Open discussion and Q&A
Come prepared:
📄 Preprint link coming soon (under review at npj Genomic Medicine)
How it works
Pan.bio Journal Club is a live discussion where we pick one paper, invite a guest scientist (often an author), and talk through it together. Just honest discussion, questions, and debate. Previous sessions featured Dr. Said Ismail (Qatar Precision Health Institute), Dr. Mamoon Ahram (University of Jordan), Dr. Rana Dajani (Hashemite University), and Dr. Joseph Shenekji on population sequencing.
Open to researchers, clinicians, pharmacists, students, and anyone curious about genomics. Come join 👋