

re:AGENT – End to End Agentic Science
WHAT IS re:AGENT
re:AGENT is a two-day build weekend focused on the infrastructure scientific agents still need: better datasets, sharper tools, and reliable ways to evaluate their work. Participants will use Paperclip, Proto, Claude, and other scientific AI tools to build systems that can take on real scientific problems and produce results worth trusting.
Paperclip turns papers, datasets, clinical trials, and biological databases into an agent-native workspace that AI systems can search, synthesize, and build upon. Proto is a design framework and infrastructure layer for generative biology, allowing builders to combine AI models and search for DNA, RNA, or protein sequences that satisfy custom criteria.
The weekend brings together engineers, scientists, computational biologists, founders, and AI researchers. Projects might include assembling a research-ready dataset that would be impractical to create by hand, along with the analysis needed to show that its findings are real. Others might involve designing a new biological system to a defined specification and testing whether it holds up against existing evidence.
The aim is not just to accelerate existing workflows, but to create the tools, datasets, and evaluation methods that make entirely new scientific questions and experiments possible.
READY TO BUILD?
If you're excited about the future of AI, agents and scientific discovery, we'll see you there...
We will close applications on Thursday, 30th of July, 12 PM PST. Spots will be confirmed on Friday, 31st of July.
WHO SHOULD ATTEND
People with the questions: scientists of all stripes. Wet lab, computational, clinical, industry. Biology, biochemistry, biophysics, chemistry, structural. Anyone with a real problem, ideally a real dataset, and the judgment to tell right from wrong results.
People who build for a living: ML engineers, software developers, and agent builders who can take a half-formed scientific problem and ship something that runs by Sunday.
No prior AI expertise required. Participants are welcome at all levels.
SCHEDULE
Day 1 — Saturday, August 15 (from 8:30 am)
Check-in, coffee & bagels
Welcome, tracks & host tool lightning talks
Ideation, pitches & team formation
Build sessions, with mentor office hours throughout
Dinner & sponsor remarks
Progress checkpoint, then Day 1 close
Day 2 — Sunday, August 16 (from 8:30 am)
Breakfast
Final build session
Submissions due, brunch & project expo
Featured talks on the future of scientific agents
Project demos & live judging
Awards, group photo & closing
Tracks
Track A: Build an AI Scientist
Build an AI agent that can carry out a defined scientific or drug-development workflow from start to finish. It should gather evidence, use relevant tools or databases, produce a structured output, and make its reasoning easy to inspect. Examples include a virtual FDA reviewer, toxicology agent, clinical trial designer, or experimental planning agent.
Track B: Build a Dataset or Meta-Analysis
What have you always wanted the literature to tell you, but could never read fast enough to find out? Draft the queries, run them across thousands of papers, sharpen and re-run until the results hold the specific pieces you care about. Then the real work: find the pattern in what you assembled that no single paper could show you, and demo that.
Track C: Build the Biological Design
Assemble a pipeline that designs biology to a spec you choose, from a single protein up to a multi-gene system. You set the constraints; the models generate candidates and evolve them toward something that could hold up in a real cell. Could the literature reveal the most promising design space for a generative model to explore? What you demo is the new biological design you made — the sequence or system that didn't exist before you built it.
Or come with a different project of your own.
Prizes will be awarded.
FAQs
Do I need a biology background or an AI background to participate?
No. We're looking for engineers with no life sciences experience as well as individuals who are in life sciences. One is helpful, but you don’t need both. The best teams usually pair technical builders with someone who knows the science.
Do I need a team before applying?
No. You can apply as a team, but you don’t have to. You can apply solo, and you'll meet potential teammates at the kickoff event.
What will I have access to during the hackathon?
Free Paperclip API access, access to Proto, Claude API credits, and compute and credits from our sponsors.
Is there a cost to attend?
The event is free to attend. Food, drinks, and compute are covered.
What happens to what I build afterward?
You keep it. Teams are free to open-source, continue building, or spin their project into something bigger.
CO-HOSTS
Supported by an incredible group of partners helping accelerate innovation in AI and science.