NGS IEG October 15th - Sara Selitsky; FlashPath

​NGS IEG October 15th - Dr. Sara Selitsky; Flashpath

​Greetings!

​Please join us on Thursday, October 15th to welcome Dr. Sara Selitsky from Flashpath in Durham, NC. Dr. Selitsky will explore animal-to-human drug concordance, including adverse events, translatability, and divergence! 🐭 ↔️ 🙂

• ​Title: Connecting animal and human drug safety: A network view of toxicity profiles

• ​Host: TBD

• ​Format: Hybrid (In-person and virtual). Lunch is provided for in-person attendees.

​Schedule:

• ​12:00 PM – 12:30 PM: Lunch & Social

• ​12:30 PM – 1:30 PM: Presentation

• ​1:30 PM – 2:00 PM: Networking

​Abstract:

​How do findings from animal toxicity studies relate to human drug safety, and what patterns emerge when we examine them across drugs? We assembled a harmonized resource of more than 100,000 toxicity findings across more than 1,000 drugs from regulatory review documents across five different government agencies. This talk will explore two complementary views of these data: animal-to-human concordance using drug labels and adverse-event reports, and network-derived toxicity profiles that reveal which effects occur together and how drugs with shared findings align with established drug classes. Bringing these views together provides a framework for examining which patterns translate to humans, where they diverge, and how drug class and biological context shape their interpretation.

​Event & Access Details

• ​RSVP here

• ​Add to Calendar: https://calendar.google.com/calendar/event?action=TEMPLATE&tmeid=Njc4OGo1bmxnZGxtdHB2bW52anQ4cmZobmQgY180MmthYXZqNDZzcHMxN2QxdDA2YjcwYXNkb0Bn&tmsrc=c_42kaavj46sps17d1t06b70asdo%40group.calendar.google.com

• ​In-Person Location:
  North Carolina Biotechnology Center
  15 T.W. Alexander Drive
  Research Triangle Park, NC 27709

• ​Zoom Meeting: https://ncbiotech.zoom.us/j/86440658342?pwd=MU9IckpYQUhHTnV6NE1UcXUvYnNXUT09

  • ​Meeting ID: 864 4065 8342

  • ​Passcode: 583621

​About NGS IEG

​The NextGen Sequencing Intellectual Exchange Group (NGS IEG) provides a forum to share methods and technologies driving biotechnology research in North Carolina across academic and private research sectors. We bring together industry leaders, academics, and students from the Research Triangle Park (RTP) area to share, discuss, and review new technologies and big-data platforms in a relaxed setting.

• ​Website & Schedule: https://www.ncbiotech.org/networking/exchange-groups/next-generation-sequencing-group

• ​LinkedIn: https://www.linkedin.com/groups/9175395/

• ​Slack: https://join.slack.com/t/ngsiegrtp/shared_invite/zt-1jzbjegfp-NaawAc2nhzK~D_Z4DlKMWw