Beyond Antigen Recognition: Outsmarting Tumor Heterogeneity

​How can we engineer cell therapies capable of overcoming tumor heterogeneity?

​In this session, Alessia Volpe, PhD - Chief Research Fellow and Senior Research Scientist in the Radiology Department at Memorial Sloan Kettering Cancer Center - will share an innovative strategy designed to address antigen heterogeneity in adoptive cell therapy.

​Drawing on over a decade of experience in translational immuno-oncology, advanced in vivo imaging, and the development of cutting-edge optical and nuclear imaging platforms, she will also discuss how multimodal imaging supports CAR-T cell design and the optimization of next-generation immunotherapies.

​💬 Moderator: Rosario De Feo, Lead of Nucleate Italy

​✨ Scientific Breakthrough is a new program by Nucleate Italy that spotlights Amazing scientists and rising innovators shaping the future of biotechnology. Each session gives young researchers and early-career scientists a platform to share high-impact work and foster dialogue across disciplines.