Desafía SF Spring 2026 Demo Day
Join us for the Desafía San Francisco Spring 2026 Startup Demo Day, featuring 8 high-growth startups expanding into the U.S. market from Spain operating in digital identity, data verification, precision oncology, AI-powered nutrition, generative AI for real estate, legaltech automation, global mobility HR tech, and enterprise sustainability intelligence.
From AI-driven fraud prevention and liquid biopsy cancer monitoring to workflow automation for law firms and personalized nutrition at scale - these founders are redefining how we verify, heal, build, and move.
Led by female founders, these startups have acquired customers spanning global enterprises, healthcare institutions, major retailers, and multinational organizations. Highlights include:
A digital identity infrastructure platform preventing AI-driven fraud with seamless, one-click verification powered by ID wallets and reusable credentials.
A data verification SaaS generating TrustScores and Evidence Graphs that make every organizational output traceable, explainable, and auditable.
A precision oncology biotech delivering ultra-sensitive minimal residual disease testing through liquid biopsy across hematological and solid tumors.
An AI-powered nutrition personalization platform helping grocery retailers and health companies guide shoppers toward healthier choices at scale.
A gen-AI platform automating feasibility studies and architectural design for real estate developers — compressing weeks of work into minutes.
A legaltech platform centralizing and automating the full legal operations workflow for law firms across any jurisdiction.
A global mobility HR tech platform consolidating international assignments, business travel compliance, and tax optimization into a single cloud-based solution.
An enterprise mobility intelligence platform combining a commute-optimization engine and incentives automation to help organizations reduce CO₂ emissions and capture financial value.
The evening will bring together VCs, corporate innovators, founders, and international partners for an engaging showcase of emerging technologies and cross-border collaboration — followed by networking over drinks and refreshments with the founders and community.
Run of Show:
🕕 5:30 PM – Doors open
🗣️ 6:30 PM – Opening remarks
🚀 6:45 PM – Startup pitches (5 minutes each)
🍸 7:45 PM – Networking reception
Space is limited, and this event is intended to meet the founders, discover emerging technologies, and connect with VCs, corporate innovators, and international partners over drinks and networking.
This event is organized by SOSA. The Desafía San Francisco program is operated by SOSA in partnership with ICEX, Red.es, and the Trade Commission of Spain in Los Angeles.
SOSA is a global open innovation company. We work with governments and corporations, building custom innovation programs to support the development and implementation of technological innovation. SOSA's accelerator programs combine mentorship from SOSA's innovation consultants, as well as in-market introductions to corporate contacts, VC investors, industry experts, and partners. Leveraging this network, SOSA creates valuable opportunities for deals, strategic partnerships, and funding for companies in its accelerator programs.
ICEX is a public business-oriented organization aimed at promoting the prosperity of the Spanish economy through internationalization. Its goals include enhancing the competitiveness of Spanish companies and their ecosystems in international markets; promoting Spain's image and productive sectors abroad; attracting and supporting foreign investment; and providing training in these areas. ICEX also promotes the international scalability of the technological and innovative entrepreneurship ecosystem through market intelligence, institutional support, and ecosystem partnerships.
Red.es is the public corporate entity attached to the Ministry of Digital Transformation and The Civil Service. It develops programs that boost the digital economy, innovation, and entrepreneurship, while training professionals and supporting SMEs and startups through the adoption of advanced digital technologies.