Discovery Series, Dr. Naeha Subramanian, Associate Professor, Institute for Systems Biology (ISB)

​Decoding Lyme Disease: Big Data Meets the Immune System

​Every year nearly half a million Americans are diagnosed with Lyme disease, yet the biology of this tick-borne infection remains elusive. Why do some people recover quickly while others face lingering symptoms despite treatment? Why do current diagnostics struggle to detect the disease?

​Dr. Naeha Subramanian’s lab uses a powerful multiomic approach—integrating thousands of data points from blood proteins, metabolites, and immune cells—to illuminate what happens inside the body during acute infection. By mapping how immune activity in infected tissues differs from what is detected in the blood, her team is uncovering clues that may lead to more accurate diagnostics, better prediction of patient outcomes, and more effective therapies.

​Dr. Subramanian will share recent discoveries and discuss how big-data biology is transforming our understanding of this complex disease and opening new opportunities for prevention, treatment, and scientific discovery.

​Agenda 

​11:30 am to 12 pm - Lunch 

​12 pm to 12:40 pm - Presentation 

​12:40 pm to 1 pm - Audience Q&A 

​About the Discovery Series: designed to bring together the state's preeminent researchers, innovative leaders, and elected officials who want to stay on top of important advancements being made in our state, each Discovery Series program includes lunch, networking time, a Q&A session, and an opportunity to meet the speaker.